| 1 | — |  | The Rest Is Science | Goalhanger | |
| 2 | — |  | Hidden Brain | Hidden Brain, Shankar Vedantam | |
| 2 | 4 |  | More or Less | BBC Radio 4 | |
| 3 | 4 | M | Mooney Goes Wild | RTÉ Radio 1 | |
| 3 | — |  | Ologies with Alie Ward | Alie Ward | |
| 4 | — |  | Science Weekly | The Guardian | |
| 4 | 5 |  | Making Sense with Sam Harris | Sam Harris | |
| 5 | — |  | Radiolab | WNYC Studios | |
| 6 | 5 |  | StarTalk Radio | Neil deGrasse Tyson | |
| 7 | 10 |  | BBC Inside Science | BBC Radio 4 | |
| 7 | 9 | S | Show Me the Science with Luke O'Neill | Newstalk | |
| 8 | — |  | Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas | Sean Carroll | |
| 8 | 12 |  | The Resetter Podcast with Dr. Mindy | Dr. Mindy Pelz | |
| 8 | 4 | B | Boring History for Sleep | Velvet | |
| 9 | 3 |  | The Infinite Monkey Cage | BBC Radio 4 | |
| 9 | 50 | N | Naturefile | RTÉ lyric fm | |
| 10 | — | F | Futureproof with Jonathan McCrea | Newstalk | |
| 13 | 11 |  | The Life Scientific | BBC Radio 4 | |
| 13 | — |  | Curious Cases | BBC Radio 4 | |
| 15 | — |  | Science Vs | Spotify Studios | |
| 16 | — | H | How I Wrote This | Brett Gordon and Karen Winterich | |
| 16 | 2 |  | NASA's Curious Universe | National Aeronautics and Space Administration (NASA) | |
| 18 | 92 | I | In Your Nature | By BirdWatch Ireland | |
| 19 | 66 |  | Theories of Everything with Curt Jaimungal | Theories of Everything | |
| 19 | — |  | Unexplainable | Vox | |
| 20 | 37 |  | The Psychology Podcast | iHeartPodcasts | |
| 21 | 143 |  | Mysterious Universe | 8th Kind | |
| 21 | — | C | CountryWide | RTÉ Radio 1 | |
| 21 | 17 |  | Choiceology with Katy Milkman | Charles Schwab | |
| 22 | — |  | The Skeptics' Guide to the Universe | Dr. Steven Novella | |
| 22 | 22 | ' | 'Mind the Kids': an ACAMH podcast | The Association for Child and Adolescent Mental Health | |
| 22 | 20 | P | Pint of Science Ireland | Pint of Science Ireland | |
| 22 | 27 |  | The Catholic Guide to Sustainable Living | Ave Maria University | |
| 22 | 33 |  | The Michael Shermer Show | Michael Shermer | |
| 23 | 83 |  | Universe Today Podcast | Fraser Cain | |
| 23 | — |  | Discovery | BBC World Service | |
| 24 | 50 | T | The Vet Pod | The Vet Pod | |
| 25 | 53 |  | Mythfits | Pionaire Podcasting | |
| 25 | — |  | Science Friday | Science Friday and WNYC Studios | |
| 26 | — |  | New Books in Critical Theory | Marshall Poe | |
| 26 | 26 |  | Sasquatch Chronicles | Sasquatch Chronicles - Bigfoot Encounters | |
| 26 | — | C | Climate change - off the record | Dr Clare Noone and Dr Róisín Moriarty | |
| 27 | 40 |  | The Naked Scientists Podcast | The Naked Scientists | |
| 27 | 4 |  | This Podcast Will Kill You | Exactly Right and iHeartPodcasts | |
| 27 | — |  | Ireland's Landscape Histories and Futures | Stephanie O'Rourke | |
| 28 | 96 |  | ExtinctZoo | ExtinctZoo | |
| 28 | — | F | Farming Today | BBC Radio 4 | |
| 28 | 26 | T | The Land Before Podcast: Fossil Histories and Paleo Mysteries | Dinosaur Ridge | |
| 29 | — |  | Paranormal Mysteries | Nic Ryan | Paranormal Mysteries Podcast | |
| 29 | 1 |  | DarkHorse Podcast | Bret Weinstein & Heather Heying | |
| 29 | 166 |  | The Astrophysics Podcast | Paul Duffell | |
| 30 | 169 |  | Planet Em | Emily McDonald | |
| 31 | — | N | Nature Fix | National Trust | |
| 31 | — | C | Conservation and Science | Tommy's Outdoors | |
| 32 | — |  | CrowdScience | BBC World Service | |
| 32 | — |  | Sensible Medicine | Sensible Medicine Authors and Editors | |
| 32 | 31 |  | That UFO Podcast | That UFO Podcast | |
| 33 | 8 |  | A Question of Science | The Francis Crick Institute | |
| 34 | — |  | Uncharted with Hannah Fry | BBC Radio 4 | |
| 34 | 151 | B | Bird Songs with Seán Ronayne | RTÉ lyric fm | |
| 35 | — | R | Richard Wiseman's On Your Mind | Podimo & TellTale | |
| 35 | — | T | The Critter Shed | Collie Ennis & Colette Kinsella for Red Hare Media | |
| 36 | — |  | Breaking Math Podcast | Autumn Phaneuf & Noah Giansiracusa | |
| 37 | 12 |  | Babbage from The Economist | The Economist | |
| 37 | — |  | The Grave Talks | Haunted, Paranormal & Supernatural | Ghost Stores, Haunted, Paranormal & Supernatural Stories | |
| 37 | — | T | The Cancer Trials Ireland Podcast | Cancer Trials Ireland | |
| 38 | 1 |  | Astrum Space | Astrum | |
| 38 | — |  | This Week in Microbiology | Vincent Racaniello | |
| 39 | — | T | The Qualitalks Podcast | Qualistery | |
| 40 | — | C | Conversations on the Pharmaceutical Industry | Reading Scientific Services Ltd | |
| 41 | — | T | The QP Diaries, by AssureBio | Dal Pawar | |
| 41 | — |  | The Brain Health Revolution Podcast | The Brain Docs | |
| 42 | 107 |  | WEAPONIZED with Jeremy Corbell & George Knapp | Jeremy Corbell and George Knapp | |
| 42 | 14 | T | The Meaning of Trees Podcast | Tom Hill | |
| 42 | — |  | We're not getting any younger... yet. | The Buck Institute | |
| 43 | — |  | Why This Universe? | Dan Hooper, Shalma Wegsman | |
| 43 | — | T | The Anatomy Nerd Podcast | Anatomy Nerd | |
| 44 | 10 |  | Mysterious Radio: Paranormal, UFO and Lore Interviews | Podcast Audio House | |
| 44 | 6 |  | Something You Should Know | Mike Carruthers | OmniCast Media | |
| 45 | — | S | Sustainably Geeky | Epically Geeky | |
| 46 | — |  | StarTalk Podcast | StarTalk Podcast | |
| 46 | 17 | T | The OT Podcast | The OT Podcast | |
| 47 | — |  | The Sustainability Agenda | Fergal Byrne | |
| 48 | 9 | P | Personlighetspodden | Jesper Cederstrand & Petri Kajonius | |
| 48 | — |  | I Know Dino: The Big Dinosaur Podcast | I KNOW DINO, LLC | |
| 49 | — | T | Tom MacSweeney's Seascapes | Tom MacSweeney | |
| 50 | — | U | Untangling the Web | Web Science Trust | |
| 51 | — |  | Constant Wonder | BYUradio | |
| 51 | — |  | Houston We Have a Podcast | National Aeronautics and Space Administration (NASA) | |
| 52 | 6 | E | Environmental Politics and Law - Audio | John Wargo | |
| 53 | 56 |  | Daniel and Kelly’s Extraordinary Universe | iHeartPodcasts | |
| 53 | — |  | Crash Course Pods: The Universe | Crash Course Pods, Complexly | |
| 58 | 31 |  | The Plodcast | Our Media | |
| 58 | — |  | The Wild with Chris Morgan | KUOW News and Information | |
| 60 | — |  | You Are Not So Smart | You Are Not So Smart | |
| 61 | — |  | The Great Simplification with Nate Hagens | Nate Hagens | |
| 62 | — |  | Sidenote by AsapSCIENCE | AsapSCIENCE | |
| 63 | 27 |  | Leaked | TFLabs | |
| 64 | — |  | Espacio en blanco | Radio Nacional | |
| 65 | 17 |  | Ask a Spaceman! | Paul M. Sutter | |
