| 1 | — |  | The Rest Is Science | Goalhanger | |
| 2 | — |  | Hidden Brain | Hidden Brain, Shankar Vedantam | |
| 3 | — |  | Radiolab | WNYC Studios | |
| 3 | 2 |  | StarTalk Radio | Neil deGrasse Tyson | |
| 3 | 4 |  | Ologies with Alie Ward | Alie Ward | |
| 4 | — |  | Making Sense with Sam Harris | Sam Harris | |
| 4 | 2 |  | The Infinite Monkey Cage | BBC Radio 4 | |
| 7 | 3 |  | The Naked Scientists Podcast | The Naked Scientists | |
| 7 | 1 |  | Science Weekly | The Guardian | |
| 8 | 3 |  | Unexplainable | Vox | |
| 8 | 5 |  | Curious Cases | BBC Radio 4 | |
| 9 | 9 |  | More or Less | BBC Radio 4 | |
| 9 | — |  | Science Vs | Spotify Studios | |
| 10 | 4 | B | Boring History for Sleep | Velvet | |
| 10 | 2 |  | The Resetter Podcast with Dr. Mindy | Dr. Mindy Pelz | |
| 11 | 29 |  | Planet Em | Emily McDonald | |
| 11 | 9 |  | Ask the Naked Scientists | Dr Chris Smith | |
| 11 | 8 |  | Google DeepMind: The Podcast | Hannah Fry | |
| 15 | — |  | The Skeptics' Guide to the Universe | Dr. Steven Novella | |
| 15 | 6 |  | Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas | Sean Carroll | |
| 16 | 7 |  | Drilled | Pushkin Industries | |
| 16 | 1 |  | Speaking of Psychology | American Psychological Association | |
| 16 | — |  | This Podcast Will Kill You | Exactly Right and iHeartPodcasts | |
| 16 | 104 |  | Unexpected Elements | BBC World Service | |
| 17 | 11 |  | Science Friday | Science Friday and WNYC Studios | |
| 17 | 67 |  | The Quanta Podcast | Quanta Magazine | |
| 18 | 4 |  | CrowdScience | BBC World Service | |
| 18 | 6 |  | Discovery | BBC World Service | |
| 18 | 45 |  | UAP Files Podcast | UAP Files Podcast | |
| 19 | 6 |  | Mysterious Radio: Paranormal, UFO and Lore Interviews | Podcast Audio House | |
| 19 | 39 | T | The Naked Scientists Podcast | The Naked Scientists | |
| 20 | 19 |  | Blurry Creatures | Blurry Creatures | |
| 20 | 14 |  | The Science of Happiness | PRX and Greater Good Science Center | |
| 20 | 6 |  | You Are Not So Smart | You Are Not So Smart | |
| 21 | — |  | BIOACTIVE | Riley D. Kirk, Ph.D. | |
| 21 | 9 |  | Tooth & Claw: True Stories of Animal Attacks | Wes Larson, Jeff Larson, Mike Smith | Daylight Media | |
| 21 | 41 | S | Science + God with Dr. G | AccessMore | |
| 22 | 7 |  | Uncharted with Hannah Fry | BBC Radio 4 | |
| 22 | 14 |  | Astrum Space | Astrum | |
| 22 | 5 |  | Something You Should Know | Mike Carruthers | OmniCast Media | |
| 22 | — |  | New Books in Critical Theory | Marshall Poe | |
| 23 | 75 |  | A Question of Science | The Francis Crick Institute | |
| 24 | 76 |  | Daniel and Kelly’s Extraordinary Universe | iHeartPodcasts | |
| 25 | 10 |  | DarkHorse Podcast | Bret Weinstein & Heather Heying | |
| 26 | 16 |  | Stuff To Blow Your Mind | iHeartPodcasts | |
| 27 | 21 |  | BBC Inside Science | BBC Radio 4 | |
| 28 | 155 |  | I Know Dino: The Big Dinosaur Podcast | I KNOW DINO, LLC | |
| 29 | 86 |  | Science Magazine Podcast | Science Magazine | |
| 29 | 8 |  | Babbage from The Economist | The Economist | |
| 29 | 136 |  | Into the Impossible With Brian Keating | Big Bang Productions Inc. | |
| 29 | 4 |  | From First Principles | Krishna Choudhary and Lester Nare | |
| 30 | 16 |  | The world, the universe and us | New Scientist | |
| 30 | 2 |  | EverydaySpy Podcast | Andrew Bustamante | |
| 30 | 29 |  | The Great Simplification with Nate Hagens | Nate Hagens | |
| 31 | 33 |  | Skeptics with a K | Skeptic Media Limited | |
| 31 | 14 |  | The Supermassive Podcast | The Royal Astronomical Society | |
| 31 | — |  | Accidental Gods | Accidental Gods | |
| 32 | 29 |  | Theories of Everything with Curt Jaimungal | Theories of Everything | |
| 33 | 141 |  | Robert Sapolsky | Father-Offspring Interviews | Robert Sapolsky | |
| 33 | 24 |  | Inner Cosmos with David Eagleman | iHeartPodcasts | |
| 36 | 2 |  | TheThinkingAtheist | The Thinking Atheist | |
| 37 | 4 |  | Why This Universe? | Dan Hooper, Shalma Wegsman | |
| 37 | 19 |  | Psychiatry & Psychotherapy Podcast | David Puder, M.D. | |
| 38 | 50 |  | People Who Read People: A Behavior and Psychology Podcast | Zachary Elwood | |
| 39 | — |  | HOLOSKY PODCAST | Holosky Podcast | |
| 40 | 87 |  | Therapist Uncensored Podcast | Sue Marriott LCSW, CGP & Ann Kelley PhD | |
| 41 | 145 |  | Overheard at National Geographic | National Geographic | |
| 41 | 12 | B | Brain Matters | Brain Matters Neuroscience | |
| 41 | 2 | T | The Soil Health Hub Podcast | Soil Health Hub | |
| 41 | 117 | T | The Vertue Podcast | Shona Vertue | |
| 42 | 9 | P | Plane Crash Diaries | Desmond Latham | |
| 42 | — |  | Templeton Ideas Podcast | John Templeton Foundation | |
| 42 | 13 | F | From Our Neurons to Yours | Wu Tsai Neurosciences Institute at Stanford University, Nicholas Weiler | |
| 43 | 9 |  | Critical Matters | Sound Physicians | |
| 43 | 1 | P | PeerView Infectious Diseases CME/CNE/CPE Audio Podcast | PVI, PeerView Institute for Medical Education | |
| 43 | — |  | The Archaeology Show | Archaeology Podcast Network | |
| 44 | 3 | G | Green Noise | CapeNature | |
| 44 | 128 |  | Intelligent Design the Future | Discovery Institute | |
| 44 | — | H | Historical Astronomy | Robert Wagner | |
| 44 | 23 |  | Lingthusiasm - A podcast that's enthusiastic about linguistics | Gretchen McCulloch and Lauren Gawne | |
| 45 | — | W | Wealth Pathways: The Affluence Science Insights Podcast | Life Management Science Labs | |
| 45 | — |  | The Nature Of with Willow Defebaugh | Atmos | |
| 45 | 15 |  | MCHD Paramedic Podcast | Montgomery County Hospital District | |
| 45 | 5 | P | Philosophy | Cambridge University | |
| 45 | 20 |  | TED Talks Science and Medicine | TED | |
| 45 | 9 | T | The Fibre Frontier | Dr Mark Ferguson | |
| 46 | — |  | Deep Seed - Regenerative Agriculture | Raphael Esterhazy | |
| 46 | 20 | T | There's No Such Thing As A Dumb Question | There's No Such Thing As A Dumb Question | |
| 46 | 49 |  | The Origins Podcast with Lawrence Krauss | Lawrence M. Krauss | |
| 47 | 2 |  | Mythfits | Pionaire Podcasting | |
| 47 | — |  | SOIL: Rewilding the Underground | Freya Mulvey | |
| 47 | 60 |  | SpaceTime with Stuart Gary | Stuart Gary | |
| 48 | — | T | The Knepp Wilding Podcast | Knepp.co.uk | |
| 48 | 41 |  | The Life Scientific | BBC Radio 4 | |
| 49 | 80 |  | La Science, CQFD | France Culture | |
| 49 | 33 |  | The Psychology Podcast | iHeartPodcasts | |
| 51 | 43 |  | Mysterious Universe | 8th Kind | |
| 51 | 19 |  | That's Just Wild | Fresh Air | |
| 52 | 19 |  | The Green Room: A Podcast from Obstetrics & Gynecology | Obstetrics & Gynecology (Green Journal) | |
| 52 | 49 |  | The Michael Shermer Show | Michael Shermer | |
